Material Safety Data Sheet: 2-Acrylamido-2-Methylpropane Sulfonic Acid (AMPS)
Identification
Product name: 2-Acrylamido-2-Methylpropane Sulfonic Acid
Common Synonyms: AMPS; 2-Methyl-2-Propenoic Acid, 2-Acrylamido-2, Methylpropane Sulfonic Acid
Chemical Formula: C7H13NO4S
CAS Number: 15214-89-8
Recommended use: Used in copolymerization for water treatment, oil drilling, textile, and paper industries
Supplier Details: Contact local distributor or manufacturer for full address and emergency contact information.
Emergency Phone Number: Local poison control center or environmental health and safety line, as provided by supplier.
Hazard Identification
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity oral (Category 5)
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; causes skin irritation; may cause respiratory irritation
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; wear protective gloves, eye and face protection.
Physical Hazards: None reported under normal conditions
Health Hazards: Dust or powder exposure can irritate skin, eyes, and respiratory tract
Environmental Hazards: Possible risk to aquatic life if large quantities released untreated into the environment.
Composition / Information on Ingredients
Chemical Name: 2-Acrylamido-2-Methylpropane Sulfonic Acid
Concentration: ≥98%
Impurities: May contain trace amounts of sodium chloride, acrylamide, and water (<2%)
Molecular weight: 207.25 g/mol
Other components: None considered hazardous under GHS.
First Aid Measures
Inhalation: Move to fresh air, keep at rest, seek medical advice if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin immediately with plenty of water, seek medical attention for persistent irritation
Eye Contact: Rinse cautiously with water for at least 15 minutes, keep eyelids open, seek immediate medical attention
Ingestion: Rinse mouth with water, do not induce vomiting, seek immediate medical guidance
Most important symptoms: Redness, irritation, soreness at point of contact or inhalation
Indication for immediate medical attention: Persistent difficulty breathing, eye damage, severe rash or allergic symptoms.
Fire-Fighting Measures
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Direct water jets can spread powder
Specific Hazards: Dust can form explosive mixtures with air at high concentrations
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective gear
Special Precautions: Keep dust to minimum, contain fire-water runoff; prevent contamination of drains and watercourses.
Accidental Release Measures
Personal Precautions: Evacuate unprotected personnel, use personal protective equipment (gloves, goggles, respirator as needed)
Environmental Precautions: Prevent material from entering soil, waterways, and drains
Methods for containment: Stop leak if without risk, collect spilled powder or crystals using appropriate tools, place in labeled container
Clean-up procedure: Use non-sparking, non-metallic tools to gather solid material, wash spill area thoroughly with water after removal
Disposal: Dispose collected waste according to local, regional, and national regulations on hazardous waste.
Handling and Storage
Handling: Handle with care to avoid generating dust, avoid contact with eyes and skin, wash hands after handling, use only in areas with proper ventilation
Do not eat or drink: In work areas where AMPS is handled
Storage: Store tightly closed in a cool, dry, well-ventilated location away from strong oxidizers and bases
Storage Temperature: Store at room temperature, do not freeze or expose to direct sunlight
Incompatible Materials: Strong oxidizing agents, strong bases, strong acids
Packaging Materials: Store in original sealed containers made from polyethylene or polypropylene; check for compatibility before repackaging.
Exposure Controls and Personal Protection
Exposure Limits: No occupational exposure limits established specifically for this chemical
Engineering Controls: Local exhaust ventilation at points of dust generation, safety showers and eyewash stations in immediate area
Personal Protection: Chemical protective gloves (nitrile, PVC), close-fitting safety goggles, long-sleeved lab coat or protective clothing
Respiratory Protection: Dust mask or half-face respirator with particulate filter for bulk handling
Hygiene Measures: Do not touch face or eyes during handling, remove and wash contaminated clothing before reuse, always wash hands before breaks and at end of shift.
Physical and Chemical Properties
Appearance: White or off-white crystalline powder
Odor: Odorless or faint non-distinct odor
Odor Threshold: Not determined
pH (1% solution): Approximately 2.0
Melting Point: 185 - 190°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Flammability: Not classified as flammable
Vapor Pressure: Negligible at 20°C
Water Solubility: Freely soluble in water
Partition coefficient (n-octanol/water): Not determined
Autoignition Temperature: No data available
Decomposition Temperature: 185 - 190°C
Relative Density: 1.3 – 1.5 g/cm³
Viscosity: Not applicable to solid material
Bulk density: Approximately 0.6 – 0.8 g/cm³
Stability and Reactivity
Chemical Stability: Stable under recommended storage and handling conditions
Reactivity: Inert under normal conditions; reacts with strong oxidizing agents and bases
Hazardous Reactions: Risk of polymerization at elevated temperatures in presence of initiators
Conditions to Avoid: High heat, sources of ignition, moisture, direct sunlight
Incompatible Materials: Strong oxidizing agents, strong bases, reducing agents
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides, acrylamide monomer fumes at decomposition temperatures
Toxicological Information
Acute Toxicity: Oral LD50 (rat) > 5,000 mg/kg indicating low acute toxicity
Skin Corrosion/Irritation: Causes irritation; prolonged or repeated contact can aggravate underlying skin conditions
Serious Eye Damage/Irritation: Causes severe eye irritation and possible injury on direct contact
Respiratory or Skin Sensitization: Expected to be non-sensitizing but may cause irritation if inhaled as dust
Germ Cell Mutagenicity: No data indicating genetic effects
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No adverse reproductive effects observed
Specific Target Organ Toxicity (Single Exposure): Not classified
Specific Target Organ Toxicity (Repeated Exposure): Not classified
Signs and Symptoms of Exposure: Coughing, sneezing, eye redness, skin itching, throat discomfort after dust exposure.
Ecological Information
Aquatic Toxicity: LC50 (fish, 96h) >100 mg/L (low acute toxicity); EC50 (daphnia) >100 mg/L
Persistence and Degradability: Moderately biodegradable; some persistence expected under anaerobic conditions
Bioaccumulation potential: Low due to high water solubility and minimal log Kow
Mobility in Soil: Highly mobile; leaches readily in aqueous environment
Other adverse effects: Large releases may cause local pH decrease and affect aquatic biota
Limited risk: To fish and microorganisms at typical commercial concentrations
Wastewater impact: Compatible with biological treatment systems if diluted; avoid large, undiluted releases.
Disposal Considerations
Disposal Methods: Dispose of contents and container in accordance with local, regional, national, and international regulations
Unused product: Collect and deliver to hazardous waste collection point; do not dispose with household waste
Contaminated Containers or Packaging: Triple rinse with water, dispose as hazardous waste or follow recycling instructions from local government
Special precautions: Protect unused material from moisture until ready to dispose; do not allow material to enter water bodies in large amounts
Sewage disposal prohibited: Without prior treatment and dilution by municipal sewage plants.
Transport Information
UN Number: Not regulated as dangerous goods
UN Proper Shipping Name: Not classified
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Marine Pollutant: Not classified
Special Precautions for Users: Avoid generating dust during loading and unloading, secure packaging to prevent leakage
Transport in bulk: Ensure vessels or trucks are compatible and lined to prevent reaction
Labelling: Standard labeling according to relevant regional regulations; Safety Data Sheet should accompany large shipments.
Regulatory Information
International Inventories: Listed on TSCA (US), EINECS/ELINCS (EU), DSL (Canada), ENCS (Japan), IECSC (China), AICS (Australia), NZIoC (New Zealand), PICCS (Philippines), and other major inventories
OSHA Hazard Communication: Classified as hazardous under OSHA Hazard Communication Standard
SARA Title III: Not listed as Extremely Hazardous Substance or subject to section 313 reporting
California Proposition 65: This material does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm
REACH Status (EU): Substance registered or pre-registered
Other Regulations: Follow all requirements by local agencies regarding workplace handling, environmental protection, and reporting obligations.
