MSDS for Shandong Tianli Pharmaceutical Co.,Ltd Dextrose Monohydrate
1. Identification
Product Name: Dextrose Monohydrate
Synonyms: Glucose Monohydrate, D-Glucose Monohydrate
Product Code: Internal reference unique to Shandong Tianli Pharmaceutical Co.,Ltd
Manufacturer: Shandong Tianli Pharmaceutical Co.,Ltd
Address: No. 25, Weiwu Road, Weifang Hi-Tech Industrial Development Zone, Shandong, China
Emergency Phone: Manufacturer’s on-call number available through corporate communication.
Recommended Uses: Pharmaceutical ingredient, nutritional supplement, food additive.
Restrictions: For manufacturing, laboratory, and commercial use only by qualified personnel.
2. Hazard Identification
Classification: Not classified as hazardous under GHS or local regulations.
Label Elements: No pictogram, warning, or hazard statement.
Physical Hazards: Dust may cause respiratory irritation. Fine powders can form explosive mixtures with air.
Health Hazards: Inhalation of dust can cause coughing or mild respiratory discomfort; ingestion in large quantities may affect blood glucose levels.
Environmental Hazards: Not expected to cause adverse environmental effects in small releases; large concentrations may contribute to BOD in water bodies.
Other: No known chronic effects or carcinogenicity.
3. Composition / Information on Ingredients
Chemical Name: Dextrose Monohydrate
CAS Number: 77938-63-7
Molecular Formula: C6H12O6•H2O
Content: Not less than 99% (by weight)
Impurities: Trace amounts of other saccharides and water.
Additives: No additives added.
EC Number: 232-467-7
4. First Aid Measures
Inhalation: Move person into fresh air; rinse nose, seek medical attention if symptoms persist.
Skin Contact: Wash with water and soap for exposed areas.
Eye Contact: Rinse with plenty of water for 10-15 minutes, remove contact lenses, consult physician if irritation develops.
Ingestion: Rinse mouth, give water to drink, do not induce vomiting, obtain medical help for large quantities or if symptoms develop.
Notes for Physician: Symptomatic treatment only.
Special Precautions: No delayed effects anticipated from normal exposure.
5. Fire-Fighting Measures
Flammability: Fine powders may combust in air clouds.
Suitable Extinguishing Media: Water spray, carbon dioxide, dry chemical, or foam.
Unsuitable Extinguishing Media: None known.
Special Hazards: Dust/air mixtures can result in explosions, may produce carbon monoxide and carbon dioxide.
Fire-Fighter Protection: Wear self-contained breathing apparatus, full protective gear to avoid inhaling dust or decomposition gases.
Equipment Precautions: Isolate area, remove ignition sources, avoid generating dust.
6. Accidental Release Measures
Personal Precautions: Use personal protective equipment including dust mask, goggles, gloves.
Environmental Precautions: Prevent spillage from entering sewers or water sources.
Cleanup Methods: Sweep or vacuum using methods that minimize dust generation, place in properly labeled containers for disposal.
Handling Spills: Wet sweeping or vacuum equipped with HEPA filter preferred for larger spills.
Disposal: Refer to Disposal Considerations.
Additional Protection: Isolate area from unnecessary personnel during cleanup.
7. Handling and Storage
Handling: Avoid generating and inhaling dust. Keep away from open flames, sparks, and sources of heat. Use in well-ventilated areas.
Storage Conditions: Store in cool, dry areas away from moisture, direct sunlight, and incompatible substances. Seal containers tightly to prevent absorption of moisture.
Packing Materials: Use food-grade polyethylene or fiber drums with inner liner.
Incompatibilities: Avoid strong oxidizers.
Special Notes: Rotate stocks to prevent over-aging. Keep work area clean and implement dust controls.
8. Exposure Controls and Personal Protection
Exposure Limits: No official occupational exposure limits for dextrose monohydrate.
Engineering Controls: Use local exhaust or general ventilation to control airbornedust levels.
Personal Protective Equipment (PPE): Dust mask (nuisance dust respirator), safety goggles, protective gloves, clean work clothing.
Hygiene Measures: Wash hands after use, change out of contaminated clothing, avoid eating or drinking near the handling area.
Environmental Controls: Monitor common dust emission points, install filtration if necessary.
9. Physical and Chemical Properties
Appearance: White crystalline powder or granules.
Odor: Odorless.
Odor Threshold: Not relevant.
pH: 4.0 – 7.0 (aqueous solution).
Melting Point: 83°C (decomposes).
Boiling Point: Not applicable.
Flash Point: Not applicable.
Flammability: Dust may be combustible.
Explosive Properties: Dust may form explosive mixtures in air.
Vapor Pressure: Negligible.
Solubility: 120 g/100 ml water at 25°C.
Partition Coefficient (n-octanol/water): Not determined.
Viscosity: Not applicable.
Auto-ignition Temperature: >400°C
Bulk Density: 0.7-0.9 g/cm³
10. Stability and Reactivity
Chemical Stability: Stable under recommended conditions.
Reactivity: May react with strong oxidizing agents.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide produced on combustion.
Possibility of Hazardous Reactions: None under normal processing.
Conditions to Avoid: Excessive heat, open flames, dust accumulation.
Materials to Avoid: Strong oxidizers like sodium hypochlorite, nitric acid.
Polymerization: Will not occur.
11. Toxicological Information
Likely Routes of Exposure: Inhalation, ingestion, skin, and eye contact.
Acute Toxicity: LD50 (oral, rat): >15000 mg/kg; practically non-toxic.
Skin Corrosion/Irritation: Not irritating.
Eye Damage/Irritation: Slightly irritating to eyes on contact with dust.
Respiratory or Skin Sensitization: Not sensitizing.
Chronic Effects: No evidence of carcinogenicity, mutagenicity, reproductive toxicity.
Other Effects: Large quantities by mouth may disturb blood glucose, otherwise low risk at typical exposure levels.
Medical Conditions Aggravated by Overexposure: Diabetes, glucose metabolism disorders.
12. Ecological Information
Ecotoxicity: Not considered hazardous to aquatic or terrestrial environments.
Aquatic Toxicity: No data indicating harm to aquatic life; material is readily biodegradable.
Persistence and Degradability: Easily broken down by natural biological processes.
Bioaccumulation: Does not bioaccumulate.
Mobility: Highly soluble in water, can move within soil profiles.
Other Adverse Effects: Rapid microbial degradation can deplete oxygen in water bodies if released in large amounts.
Disposal to Waterways: Avoid dumping large quantities.
13. Disposal Considerations
Product Disposal: Dispose in accordance with national and local regulations. Typically suitable for landfill or incineration alongside regular non-hazardous chemical waste.
Recycling: Not feasible for material used in process cycles; disposal recommended after contamination.
Packaging: Thoroughly clean and recycle or dispose of packaging in accordance with relevant regulations.
Sewage Disposal: Small laboratory quantities can go to drain if allowed locally; do not discharge excessive quantities.
14. Transport Information
UN Number: Not classified.
UN Proper Shipping Name: Not regulated for transport.
Transport Hazard Class: Not subject to ADR/RID/IMDG/IATA regulations.
Packing Group: Not assigned.
Special Precautions for User: Secure containers during transit, avoid extreme temperatures and moisture.
Environmental Hazards: Not classified as environmentally hazardous for transportation.
Transport in Bulk: No restriction.
15. Regulatory Information
International Inventories: Listed on major chemical inventories such as EINECS (EU), TSCA (USA), DSL (Canada), AICS (Australia).
Regulatory Status: Not classified as hazardous according to EC Regulation 1272/2008 (CLP) or OSHA Hazard Communication Standard.
Workplace Regulations: No workplace exposure limits specified.
Food and Pharmaceutical Regulation: Approved for use as food additive and pharmaceutical excipient according to local and international standards.
Other Regulations: Observe national and regional laws regarding chemical, pharmaceutical, and food handling.
Restrictions: Not for use in products intended for parenteral administration without appropriate purification.
