Material Safety Data Sheet for Shandong Tianli Pharmaceutical Co., Ltd Vitamin C
Identification
Product Name: Vitamin C
Synonyms: L-Ascorbic Acid, Ascorbic Acid, C6H8O6
Manufacturer: Shandong Tianli Pharmaceutical Co., Ltd
Contact Information: 12 Qilu Avenue, Shandong High Tech Zone, China. Phone: +86-xxxxx
Recommended Use: Food additive, pharmaceutical ingredient, antioxidant in industrial processes
Chemical Formula: C6H8O6
CAS Number: 50-81-7
Emergency Telephone: +86-xxxxx
Hazard Identification
GHS Classification: Not classified as hazardous.
Hazard Pictograms: No pictogram required.
Signal Word: None
Hazard Statements: May cause mild eye, skin, or respiratory irritation in sensitive individuals.
Precautionary Statements: Avoid inhaling dust. Prevent direct contact with eyes. Practice good industrial hygiene.
Potential Health Effects: Coughing, sneezing, minor redness on skin or in eyes.
Environmental Hazards: Low ecological risk, not expected to bioaccumulate or persist.
Other Hazards: Dust may present slight explosion risk in high concentrations combined with air.
Composition / Information on Ingredients
Chemical Name: L-Ascorbic Acid (Vitamin C)
CAS Number: 50-81-7
Concentration: Not less than 99.0%
Impurities: Trace amounts of moisture, possible mineral residues below 0.1%.
Molecular Weight: 176.12 g/mol
Additives or Preservatives: None present in finished product.
First Aid Measures
Inhalation: Move person to fresh air, ensure comfortable breathing. Seek medical attention if coughing or respiratory symptoms persist.
Eye Contact: Flush eyes with running water for fifteen minutes, lifting eyelashes to remove particles. Remove contact lenses if used. Consult medical professional for sustained irritation.
Skin Contact: Wash area with mild soap and water. Remove contaminated clothing and launder before reuse.
Ingestion: Rinse mouth with water. Drink plenty of water. Rare for serious symptoms unless predisposing conditions exist.
Most Important Symptoms and Effects: Potential throat dryness, skin dryness or redness, mild headache in poorly ventilated settings.
Fire-Fighting Measures
Suitable Extinguishing Media: Use water spray, dry powder, carbon dioxide, or foam for small fires.
Unsuitable Extinguishing Media: High-pressure water streams can disperse powders and increase visibility hazards.
Specific Hazards: Fine dust can create combustibility risk; decomposition produces carbon oxides.
Protective Equipment for Firefighters: Use self-contained breathing apparatus. Full protective gear recommended.
Firefighting Instructions: Apply media from upwind position. Remove containers from fire zone if safe. Cool surroundings with water spray.
Accidental Release Measures
Personal Precautions: Wear dust mask, protective goggles, and gloves. Secure adequate ventilation in spill area.
Containment: Prevent powder from entering water bodies or sewers.
Spill Clean-Up Methods: Sweep or scoop into containers for disposed use or recycling. For small spills, use wet methods to limit dust.
Environmental Precautions: Avoid unnecessary discharge into the environment or waterway. Notify local authorities if large amounts reach drains or rivers.
Emergency Procedures: Restrict unprotected personnel from area. Clean thoroughly to prevent residue.
Handling and Storage
Safe Handling Procedures: Minimize dust formation. Use local exhaust and dust collection equipment. Wear protective apparel.
Advice on General Occupational Hygiene: Wash hands after handling. Remove and wash contaminated clothing before reuse. No eating, drinking, or smoking in work area.
Storage Requirements: Keep container tightly sealed away from moisture and direct sunlight. Store in dry, cool, and well-ventilated location.
Incompatible Materials: Strong oxidizers, strong bases, iron, copper, and metals that may catalyze oxidation.
Recommended Container Materials: Original packaging, glass, or HDPE containers provide best barrier.
Exposure Controls and Personal Protection
Occupational Exposure Limits: No specific limits provided for Vitamin C. Nuisance dust limits apply: 10 mg/m³ (total dust), 3 mg/m³ (respirable dust) as regulated.
Engineering Controls: Provide local exhaust ventilation at process points. Use enclosed handling systems where feasible.
Personal Protective Equipment:
- Respiratory: NIOSH-approved dust mask or respirator in dusty areas.
- Eye: Chemical safety goggles recommended.
- Skin: Protective gloves and long-sleeve clothing to avoid irritation.
Environmental Exposure Controls: Filter or scrub vented dust before releasing to environment. Spill kits should be available.
Physical and Chemical Properties
Appearance: White to pale yellow crystalline powder
Odor: Odorless or faintly acidic
Odor Threshold: Not applicable
pH: 2.1 to 2.6 (5% aqueous solution)
Melting Point: 190°C, dec.
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable
Evaporation Rate: Not volatile
Flammability: Not flammable as sold, combustible dust hazard possible
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Relative Density: 1.65 g/cm³
Solubility: Very soluble in water, sparingly soluble in ethanol, practically insoluble in chloroform and ether
Partition Coefficient (n-octanol/water): -2.0 (estimated)
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: >190°C
Viscosity: Not applicable
Stability and Reactivity
Chemical Stability: Stable under normal storage and handling conditions.
Possibility of Hazardous Reactions: Rapid oxidation in presence of air, metals, and especially iron and copper.
Conditions to Avoid: Heat, sunlight, moisture, sources of ignition, contact with oxidizing and alkaline substances.
Incompatible Materials: Alkalis, oxidizing agents, metal ions such as copper and iron.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, small amounts of organic acids may form.
Toxicological Information
Acute Toxicity: Oral LD50 in rats >12,000 mg/kg, indicating very low acute toxicity.
Skin Corrosion/Irritation: Mild irritation possible with prolonged skin contact.
Serious Eye Damage/Irritation: Mild and reversible irritation upon direct exposure.
Respiratory/Skin Sensitization: Not a known sensitizer.
Germ Cell Mutagenicity: Not mutagenic based on standard assays.
Carcinogenicity: Not listed as carcinogen (IARC, NTP, OSHA, ACGIH).
Reproductive Toxicity: No evidence of reproductive toxicity at typical exposure.
Specific Target Organ Toxicity – Single Exposure: No known effects.
Specific Target Organ Toxicity – Repeated Exposure: Not established; no cumulative toxicity expected.
Aspiration Hazard: Not an aspiration hazard.
Ecological Information
Ecotoxicity: Practically non-toxic to aquatic organisms.
Persistence and Degradability: Readily biodegradable. Half-life in surface water less than 24 hours due to rapid oxidation.
Bioaccumulative Potential: Not bioaccumulative; log Kow is -2.0.
Mobility in Soil: High mobility, believed to undergo rapid biodegradation in soil and water.
Other Adverse Effects: High levels may cause temporary decrease in aquatic pH if discharged in bulk.
Disposal Considerations
Waste Treatment Methods: Sweep up powder and place into appropriate containers for disposal or recovery.
Product Disposal: Dispose of product according to local, regional, and national regulations. Vitamin C usually classified as non-hazardous waste.
Packaging Disposal: Containers can be recycled after thorough cleaning. Empty containers should not be reused for food or pharmaceuticals.
Precautions: Do not introduce large amounts into waterways.
Transport Information
UN Number: Not classified as dangerous for transport.
UN Proper Shipping Name: Vitamin C, not regulated.
Transport Hazard Class(es): Not applicable
Packing Group: Not applicable
Environmental Hazards: Not a marine pollutant
Special Precautions for User: Secure loads to avoid dust emission from containers or bags.
Transport in Bulk: No special bulk requirements or restrictions apply.
Regulatory Information
Safety, Health, and Environmental Regulations: Listed in major chemical inventories including EU, USA, Canada, China.
OSHA Status (USA): Not regulated as hazardous.
TSCA (USA): All ingredients listed or are compliant.
REACH Status (EU): Complies as substance for food and pharma.
Other Regulations: Compliant with food additive standards in China, USA, and EU.
Label Requirements: Standard chemical labeling; include batch, expiry, and handling instructions in workplace settings.
Restrictions: No use or transport restrictions under typical industrial or commercial practices.
